Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801878 | 0.82 | TAAR1 (0.39) | HTR2CHTR2AHTR2BTAAR1RAB9A | |
| SCHEMBL23573950 | 0.79 | LTA4H (0.39) | LTA4HNPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL30801858 | 0.78 | SLC6A2 (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL30801735 | 0.76 | HTR2A (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL30801854 | 0.76 | ZDHHC9 (0.38) | — | |
| SCHEMBL30801866 | 0.75 | POLB (0.44) | TAAR1 | |
| SCHEMBL30801806 | 0.74 | HTR2A (0.35) | HTR2CHTR2AHTR2B | |
| SCHEMBL30801804 | 0.72 | HTR2C (0.42) | HTR2CHTR2AHTR2BTAAR1 | |
| SCHEMBL30801824 | 0.72 | HSD11B1 (0.34) | HTR2CHTR2AHTR2BDPP4 | |
| SCHEMBL30801792 | 0.72 | HSD11B1 (0.36) | HTR2CHTR2AHTR2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |