Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801854 | 0.88 | ZDHHC9 (0.38) | — | |
| SCHEMBL30801792 | 0.86 | HSD11B1 (0.36) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL30801735 | 0.86 | HTR2A (0.37) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL30801876 | 0.85 | DRD2 (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL30801858 | 0.85 | SLC6A2 (0.40) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL30801824 | 0.84 | HSD11B1 (0.34) | DPP4HTR2AHTR2CHTR2B | |
| SCHEMBL30801898 | 0.82 | HTR2C (0.37) | TAAR1DPP4RAB9AHTR2AHTR2C | |
| SCHEMBL30801851 | 0.79 | HTR2C (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL30801866 | 0.78 | POLB (0.44) | TAAR1KMT2A | |
| SCHEMBL23574131 | 0.76 | DPP4 (0.39) | DPP4RAB9ADAOKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |