Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14933431 | 0.83 | TSHR (0.56) | TSHRALDH1A1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL29959661 | 0.83 | TSHR (0.70) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL307312 | 0.83 | TSHR (0.70) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4728649 | 0.83 | ALDH1A1 (0.54) | TSHRALDH1A1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL195311 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL50994 | 0.82 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL7369896 | 0.82 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL31258847 | 0.82 | GPR35 (0.58) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL391265 | 0.82 | GPR35 (0.58) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL30013910 | 0.81 | ALDH1A1 (0.61) | TSHRALDH1A1SMN1; SMN2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 451 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253271-B | Method for preparing 2-amino-3-nitrobenzoic acid methyl ester | 浙江聚贤医药科技有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-111253271-A | Method for preparing 2-amino-3-nitrobenzoic acid methyl ester | 浙江聚贤医药科技有限公司 | 2020-06-09 | — | — | CN | claimed |
| WO-2008012852-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTS | S.I.M.S. S.r.l. - SOCIETÀ ITALIANA MEDICINALI SCANDICCI (IT) | 2008-01-31 | — | — | WO | claimed |
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | BOEHRINGER INGELHEIM INT (DE) | 2026-03-19 | — | — | US | disclosed |
| US-12552757-B2 | NRF2-activating compound | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2026-02-17 | — | — | US | disclosed |
| US-12398146-B2 | Heterobicyclic amides as inhibitors of CD38 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-08-26 | — | — | US | disclosed |
| CN-116143628-B | Preparation method of nitrobenzamide | 南通泰禾化工股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| CN-114835621-B | Imine IDO inhibitor and preparation and application thereof | 江苏天士力帝益药业有限公司 | 2025-03-18 | — | — | CN | disclosed |
| EP-4219460-B1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA INC (US) | 2025-02-26 | — | — | EP | disclosed |
| US-12234220-B2 | Immunomodulatory compounds | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| CN-1195985-A | Benzimidazole compounds | UNIV NEWCASTLE VENTURES LTD (GB) | 1998-10-14 | — | — | CN | disclosed |
| EP-0841924-A1 | BENZIMIDAZOLE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 1998-05-20 | — | — | EP | disclosed |
| US-5635525-A | DIAGNOSTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-03 | — | — | US | disclosed |
| WO-1997004771-A1 | BENZIMIDAZOLE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 1997-02-13 | — | — | WO | disclosed |
| US-5444068-A | Imidazopyridine derivatives as angiotensin II receptor antagonists, pharmaceuticals, and treatment of hypertension therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |
| CN-1070646-A | Imidazo-fused iso and heterocycle, their preparation method contains their composition and their application | HOECHST AG (DE) | 1993-04-07 | — | — | CN | disclosed |
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12398146-B2 | Heterobicyclic amides as inhibitors of CD38 | CD38, PARP12, ENTPD2 | TSHR 3250/4885ALDH1A1 361/4885SMN1; SMN2 4790/4885 |
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | CD38, CD22, CD79B | TSHR 182/4885ALDH1A1 877/4885SMN1; SMN2 3935/4885 |
| US-12234220-B2 | Immunomodulatory compounds | CRBN, CD47, CD58 | TSHR 4538/4885ALDH1A1 3939/4885SMN1; SMN2 880/4885 |
| US-12552757-B2 | NRF2-activating compound | NFE2L2, NFE2, KEAP1 | TSHR 2086/4885ALDH1A1 790/4885SMN1; SMN2 2850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.