Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | WNT3 | P56703 | 1/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LHCGR | P22888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833432 | 0.91 | EPHX2 (0.37) | LMNAEPHX2ALDH1A1RORCMEN1 | |
| SCHEMBL17942345 | 0.84 | CA12 (0.38) | LMNAEPHX2ALDH1A1KDM4ERORC | |
| SCHEMBL30833514 | 0.81 | GPR119 (0.44) | ALDH1A1KDM4EMEN1KMT2AWNT3 | |
| Trifluoroacetic Acid SCHEMBL30833404 | 0.79 | RORC (0.40) | LMNAEPHX2ALDH1A1RORCMEN1 | |
| SCHEMBL30833427 | 0.77 | RORC (0.36) | LMNAEPHX2ALDH1A1RORCWNT3 | |
| SCHEMBL30833456 | 0.75 | RORC (0.35) | LMNAEPHX2ALDH1A1RORCWNT3 | |
| SCHEMBL17942348 | 0.75 | CA12 (0.37) | EPHX2RORCNAMPT | |
| SCHEMBL30833479 | 0.75 | CA12 (0.37) | EPHX2RORCNAMPT | |
| SCHEMBL30833383 | 0.75 | MEN1 (0.42) | LMNAEPHX2ALDH1A1RORCMEN1 | |
| SCHEMBL19996432 | 0.73 | CA12 (0.40) | LMNAEPHX2RORCNAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |