Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30013856 | 0.89 | FAAH (0.56) | KMT2AFAAHCNR2NPC1RAB9A | |
| SCHEMBL2542357 | 0.82 | TAS1R3 (0.68) | KCNA3KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL30848446 | 0.80 | CTSD (0.58) | KMT2AFAAHCNR2NPC1RAB9A | |
| SCHEMBL11236668 | 0.78 | RAB9A (0.71) | KMT2ANPC1RAB9AMEN1TAS1R3 | |
| SCHEMBL30848554 | 0.77 | KMT2A (0.54) | KMT2AFAAHCNR2NPC1RAB9A | |
| SCHEMBL30855447 | 0.77 | KMT2A (0.54) | KMT2AFAAHCNR2NPC1RAB9A | |
| SCHEMBL593297 | 0.76 | HTR4 (0.58) | KCNA3KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL13944687 | 0.76 | LRRK2 (0.47) | KMT2ACNR2MEN1TAS1R3TAS1R1 | |
| SCHEMBL13175842 | 0.76 | LRRK2 (0.47) | KMT2ACNR2MEN1TAS1R3TAS1R1 | |
| SCHEMBL15880704 | 0.75 | CTSD (0.55) | KMT2AFAAHCNR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |