Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855447 | 1.00 | KMT2A (0.54) | KMT2ACTSDFAAHCNR2NPC1 | |
| SCHEMBL13310007 | 0.85 | CTSD (0.54) | KMT2ACTSDFAAHCNR2NPC1 | |
| SCHEMBL2542357 | 0.84 | TAS1R3 (0.68) | KMT2ACTSDNPC1STAT3TAS1R3 | |
| SCHEMBL29954061 | 0.84 | CTSD (0.55) | KMT2ACTSDFAAHCNR2NPC1 | |
| SCHEMBL30013856 | 0.81 | FAAH (0.56) | KMT2ACTSDFAAHCNR2NPC1 | |
| SCHEMBL11236668 | 0.81 | RAB9A (0.71) | KMT2ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL15880704 | 0.81 | CTSD (0.55) | KMT2ACTSDFAAHCNR2NPC1 | |
| SCHEMBL30848490 | 0.80 | NPC1 (0.65) | KMT2ANPC1SMN1; SMN2MEN1RAB9A | |
| SCHEMBL31419554 | 0.78 | GAA (0.55) | KMT2ANPC1SMN1; SMN2MEN1RAB9A | |
| SCHEMBL593297 | 0.78 | HTR4 (0.58) | KMT2ACTSDNPC1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |