Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23985288 | 0.81 | ALDH1A1 (0.57) | DGAT2ALDH1A1TSHRNPSR1TAS1R3 | |
| SCHEMBL30558743 | 0.81 | ALDH1A1 (0.57) | DGAT2ALDH1A1TSHRNPSR1TAS1R3 | |
| SCHEMBL4886080 | 0.80 | ROCK2 (0.63) | ALDH1A1TSHRNPSR1TAS1R3TAS1R1 | |
| SCHEMBL8759043 | 0.79 | HPGD (0.70) | ALDH1A1TSHRNPSR1SMN1; SMN2TAS1R3 | |
| SCHEMBL29937072 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRNPSR1TAS1R3TAS1R1 | |
| SCHEMBL13450633 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRNPSR1TAS1R3TAS1R1 | |
| SCHEMBL4916970 | 0.76 | HPGDS (0.65) | ALDH1A1TSHRNPSR1SMN1; SMN2TAS1R3 | |
| SCHEMBL17571783 | 0.76 | DGAT2 (1.00) | DGAT2 | |
| Boric Acid SCHEMBL6313250 | 0.76 | TAS1R3 (0.65) | ALDH1A1TSHRNPSR1SMN1; SMN2TAS1R3 | |
| SCHEMBL13545204 | 0.75 | HPGD (0.65) | ALDH1A1TSHRNPSR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152713-A | Tricyclic aryl derivatives and compositions and methods thereof | 昂胜医疗科技公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-4561562-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026128-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |