Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759043 | 0.82 | HPGD (0.70) | ALDH1A1TSHRNPSR1MAPTTAS1R3 | |
| SCHEMBL5413451 | 0.81 | MAPT (0.62) | ROCK2ALDH1A1TSHRNPSR1ROCK1 | |
| SCHEMBL13450633 | 0.80 | ALDH1A1 (0.60) | ROCK2ALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL30856041 | 0.80 | DGAT2 (0.61) | ROCK2ALDH1A1TSHRNPSR1MAPT | |
| Boric Acid SCHEMBL6313250 | 0.79 | TAS1R3 (0.65) | ALDH1A1TSHRNPSR1MAPTTAS1R3 | |
| SCHEMBL5212964 | 0.78 | ALDH1A1 (0.65) | ROCK2ALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL13556407 | 0.78 | ALDH1A1 (0.58) | ROCK2ALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL18415441 | 0.78 | TAS1R3 (0.67) | ALDH1A1TSHRNPSR1MAPTTAS1R3 | |
| SCHEMBL2264852 | 0.77 | ALDH1A1 (0.55) | ROCK2ALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL5329065 | 0.77 | LMNA (0.60) | ROCK2ALDH1A1TSHRNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064690-A1 | PYRAZOLE-AMIDES AND -SULFONAMIDES | ICAGEN, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-7223782-B2 | Pyrazole-amides and -sulfonamides | ICAGEN, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20050049237-A1 | Pyrazole-amides and -sulfonamides | ICAGEN, INC. (US) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064690-A1 | PYRAZOLE-AMIDES AND -SULFONAMIDES | SCN3A, TRPV3, HCN3 | ROCK2 4342/4885ALDH1A1 3589/4885TSHR 3666/4885 |
| US-20050049237-A1 | Pyrazole-amides and -sulfonamides | SCN3A, TRPV3, HCN3 | ROCK2 4342/4885ALDH1A1 3589/4885TSHR 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.