SCHEMBL30869419

SCHEMBL30869419

O=C(CN1CCOC(C(F)(F)F)C1)N1c2ccc(Br)cc2Oc2cc(Br)ccc21

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 17/20 0.35
KCNH2 Q12809 2/20 0.35
NR1I2 O75469 1/20 0.35
XIAP P98170 1/20 0.35
BIRC2 Q13490 1/20 0.35
CACNA1C Q13936 1/20 0.34
GRM3 Q14832 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869377 0.81 PIM1 (0.39) GRM2KCNH2NR1I2CACNA1CGRM3
SCHEMBL30869615 0.71 DPP4 (0.50)
SCHEMBL30869767 0.69 TSHR (0.47) LMNA
SCHEMBL30869661 0.69 WNT1 (0.35)
SCHEMBL30869494 0.68 CUL4A (0.33) XIAPBIRC2LMNA
SCHEMBL30869434 0.67 CASP2 (0.45)
SCHEMBL30869638 0.63 PIM1 (0.39) GRM2
SCHEMBL9419650 0.62 HTT (0.54) LMNA
SCHEMBL17340706 0.60 DRD4 (0.57)
SCHEMBL30869597 0.60 PIM1 (0.50) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 GRM2 373/4885KCNH2 851/4885NR1I2 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.