SCHEMBL30869669

SCHEMBL30869669

CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2CCN1c2ccc(-c3cccc4[nH]ncc34)cc2Sc2cc(-c3cccc4[nH]ncc34)ccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.36
KDR P35968 2/20 0.36
FGFR1 P11362 1/20 0.36
FGFR2 P21802 1/20 0.36
FGFR4 P22455 1/20 0.36
FGFR3 P22607 1/20 0.36
PARP1 P09874 1/20 0.36
SPR P35270 1/20 0.34
MAP4K1 Q92918 1/20 0.34
CREBBP Q92793 1/20 0.34
RET P07949 2/20 0.34
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
KCNK3 O14649 3/20 0.33
KCNK9 Q9NPC2 3/20 0.33
BRAF P15056 3/20 0.33
AURKA O14965 1/20 0.33
ROCK2 O75116 1/20 0.33
ERBB2 P04626 1/20 0.33
CSF1R P07333 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869774 0.90 PARP1 (0.38) ABL1KDRFGFR1FGFR2FGFR4
SCHEMBL30869697 0.85 BRAF (0.42) ABL1RETBRAF
SCHEMBL30869797 0.82 FGFR1 (0.39) ABL1KDRFGFR1FGFR2FGFR4
SCHEMBL30869536 0.78 HSD11B1 (0.40) KDRFGFR1FGFR2FGFR4FGFR3
SCHEMBL30869490 0.77 PIK3CD (0.42) ABL1KDRFGFR1FGFR2FGFR4
SCHEMBL30869457 0.77 PIK3CD (0.42) ABL1KDRFGFR1FGFR2FGFR4
SCHEMBL30869706 0.75 CHRNA7 (0.38) ABL1RETBRAF
SCHEMBL30869525 0.75 ATR (0.35) KDRFGFR1FGFR2FGFR4FGFR3
SCHEMBL30869548 0.74 BRAF (0.42) ABL1CREBBPRETBRAF
SCHEMBL30869668 0.71 NUDT1 (0.39) ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 ABL1 826/4885KDR 2528/4885FGFR1 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.