Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877433 | 0.83 | ALDH3A1 (0.40) | ALDH1A1KDM4EGAANOD1HTT | |
| SCHEMBL30877263 | 0.78 | ALDH3A1 (0.42) | ALDH1A1KDM4EGAANOD1HTT | |
| SCHEMBL28231808 | 0.73 | MEN1 (0.41) | ALDH1A1KDM4EGAAL3MBTL1POLB | |
| SCHEMBL23632474 | 0.69 | MEN1 (0.44) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL30877366 | 0.69 | L3MBTL1 (0.42) | ALDH1A1KDM4EGAANOD1HTT | |
| SCHEMBL28055302 | 0.68 | HTR3A (0.41) | ALDH1A1KDM4EGAAPOLBMAPT | |
| SCHEMBL28230815 | 0.68 | KMT2A (0.47) | ALDH1A1KDM4EGAAHTTPOLB | |
| SCHEMBL29505790 | 0.68 | HPGDS (0.49) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL28718516 | 0.68 | HPGDS (0.49) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL29505627 | 0.67 | KMT2A (0.42) | ALDH1A1KDM4EGAAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |