Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 6/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MCTS1 | Q9ULC4 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091908 | 0.89 | L3MBTL1 (0.47) | LMNAKLKB1SCD5ALDH1A1POLB | |
| SCHEMBL15310228 | 0.84 | HSD17B10 (0.49) | LMNAKLKB1MEN1KMT2AALDH1A1 | |
| SCHEMBL3093669 | 0.83 | TGM2 (0.44) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL13153130 | 0.81 | LMNA (0.44) | HPGDLMNAKLKB1SLC16A3SLC16A1 | |
| SCHEMBL3089049 | 0.81 | LMNA (0.50) | LMNAKLKB1RAB9ANPC1ALDH1A1 | |
| SCHEMBL3093110 | 0.81 | ALDH1A1 (0.47) | HPGDLMNAKLKB1SLC16A3SLC16A1 | |
| SCHEMBL3097121 | 0.80 | ALDH1A1 (0.50) | LMNAMEN1KMT2AALDH1A1ATM | |
| SCHEMBL3090463 | 0.80 | ERCC5 (0.46) | SLC16A3SLC16A1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3096925 | 0.79 | TSHR (0.41) | HPGDLMNAKMT2AALDH1A1GAA | |
| SCHEMBL15014079 | 0.79 | LMNA (0.47) | HPGDLMNAKLKB1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461209-B2 | Malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20100228026-A1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228026-A1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | REN, AGTR2, AGTR1 | HPGD 1736/4885LMNA 3803/4885KLKB1 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.