Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704348 | 0.78 | ACHE (0.67) | APAF1ACHESIGMAR1 | |
| SCHEMBL11604609 | 0.76 | APAF1 (0.98) | APAF1HDAC1HDAC6BAZ2BACHE | |
| SCHEMBL16335515 | 0.73 | SIGMAR1 (0.68) | APAF1ACHESIGMAR1 | |
| SCHEMBL29171353 | 0.72 | BAZ2B (0.79) | APAF1HDAC1HDAC6BAZ2BACHE | |
| SCHEMBL30945718 | 0.72 | BAZ2B (0.60) | APAF1HDAC1HDAC6BAZ2BACHE | |
| SCHEMBL2186097 | 0.71 | L3MBTL1 (0.70) | BAZ2BACHESIGMAR1 | |
| SCHEMBL30095920 | 0.71 | SIGMAR1 (0.62) | APAF1ACHESIGMAR1 | |
| SCHEMBL27246711 | 0.71 | ACHE (0.63) | APAF1HDAC1HDAC6BAZ2BACHE | |
| Hydrochloric Acid SCHEMBL11846883 | 0.70 | APAF1 (0.85) | APAF1HDAC1HDAC6BAZ2BACHE | |
| Carvotroline SCHEMBL350602 | 0.70 | SIGMAR1 (0.88) | ACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | DCAF1, DDB1, CUL4A | APAF1 751/4885HDAC1 671/4885HDAC6 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.