SCHEMBL309536

SCHEMBL309536

CC1(C)C2CCC1(C)C(OC(=O)c1ccccc1)C2

nearest known ligand 0.78

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.78
MAPK1 P28482 2/20 0.78
KMT2A Q03164 2/20 0.78
CYP2C19 P33261 1/20 0.64
MEN1 O00255 1/20 0.61
CYP19A1 P11511 2/20 0.54
ELANE P08246 2/20 0.50
SHBG P04278 1/20 0.50
LMNA P02545 2/20 0.48
ALDH1A1 P00352 1/20 0.48
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
XBP1 P17861 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29022975 1.00 MAPT (0.78) MAPTMAPK1KMT2ACYP2C19MEN1
SCHEMBL31540152 0.93 MAPT (0.89) MAPTMAPK1KMT2ACYP2C19MEN1
SCHEMBL20100924 0.88 MAPT (1.00) MAPTMAPK1KMT2ACYP2C19MEN1
SCHEMBL28880629 0.88 MAPT (1.00) MAPTMAPK1KMT2ACYP2C19MEN1
SCHEMBL17951346 0.86 MAPT (0.79) MAPTMAPK1KMT2ACYP2C19MEN1
SCHEMBL20100948 0.86 MAPT (0.79) MAPTMAPK1KMT2ACYP2C19MEN1
SCHEMBL20100930 0.86 MAPT (0.74) MAPTMAPK1KMT2ACYP2C19MEN1
Acetic Acid SCHEMBL27666787 0.86 MAPT (0.63) MAPTMAPK1KMT2ACYP2C19MEN1
SCHEMBL28793590 0.85 MAPT (0.77) MAPTMAPK1KMT2ACYP2C19MEN1
SCHEMBL8164460 0.85 MAPT (0.62) MAPTMAPK1KMT2ACYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111041828-A Lasting antibacterial polypropylene non-woven fabric and preparation method thereof 曾艳清 2020-04-21 CN claimed
CN-111041828-A Lasting antibacterial polypropylene non-woven fabric and preparation method thereof 曾艳清 2020-04-21 CN disclosed
US-8349781-B2 Fluid reservoir HENKEL AG & CO. KGAA (DE) 2013-01-08 US disclosed
US-20120093902-A1 FLUID RESERVOIR HENKEL AG & CO. KGAA (DE) 2012-04-19 US disclosed
US-20120077728-A1 FLUID RESERVOIR HENKEL AG & CO. KGAA (DE) 2012-03-29 US disclosed
US-8093197-B2 Fluid reservoir HENKEL AG & CO. KGAA (DE) 2012-01-10 US disclosed
CN-102285886-A (+)-2-bornyl chlorobenzoate and preparation method and use thereof 2011-12-21 CN disclosed
CN-102276469-A (+)-4-methoxy bornyl benzoate as well as preparation method and application thereof 2011-12-14 CN disclosed
US-7884063-B2 perfume emulsions, for use in dryer; aromatherapy; spray containers, textile cleaning kits HENKEL AG & CO. KGAA (DE) 2011-02-08 US disclosed
US-20100047198-A1 Textile Scenting HENKEL AG & CO., KGAA (DE) 2010-02-25 US disclosed
US-20100022437-A1 Liquid Support HENKEL AG & CO. KGAA (DE) 2010-01-28 US disclosed
US-20090035337-A1 Fluid Reservoir HENKEL AG & CO. KGAA (DE) 2009-02-05 US disclosed
US-20080221003-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-09-11 US disclosed
US-20080207481-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-28 US disclosed
US-20080207476-A1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCE PROPERTIES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035337-A1 Fluid Reservoir CD44, VCL, PEF1 MAPT 708/4885MAPK1 3655/4885KMT2A 4231/4885
US-20100022437-A1 Liquid Support GYS2, GYS1, SLC18A1 MAPT 964/4885MAPK1 4097/4885KMT2A 4698/4885
US-20120077728-A1 FLUID RESERVOIR CD44, VCL, PEF1 MAPT 708/4885MAPK1 3655/4885KMT2A 4231/4885
US-20120093902-A1 FLUID RESERVOIR CD44, VCL, PEF1 MAPT 708/4885MAPK1 3655/4885KMT2A 4231/4885
US-20100047198-A1 Textile Scenting CUTA, LCT, LIPA MAPT 1821/4885MAPK1 4412/4885KMT2A 699/4885
US-20080207476-A1 PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCE PROPERTIES DSC1, DSG1, PIEZO1 MAPT 1508/4885MAPK1 3068/4885KMT2A 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.