Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964242 | 0.75 | DRD2 (0.62) | HTR1AMAPK1MEN1KMT2ADRD2 | |
| SCHEMBL30964248 | 0.74 | DRD2 (0.68) | HTR1AMEN1KMT2ADRD2HTR2A | |
| SCHEMBL3799756 | 0.73 | OPRK1 (0.58) | HTR7DRD2HTR2ADRD3ADAMTS5 | |
| SCHEMBL30964278 | 0.72 | CXCR3 (0.55) | HTR1AMAPK1MEN1KMT2ADRD2 | |
| SCHEMBL28616498 | 0.71 | HTR1A (0.58) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL30964256 | 0.71 | HTR1A (0.56) | HTR1AHTR7MAPK1MEN1KMT2A | |
| SCHEMBL28972664 | 0.70 | ADAMTS5 (0.61) | HTR7MEN1KMT2ADRD2HTR2A | |
| SCHEMBL9405381 | 0.69 | MEN1 (0.48) | HTR7MAPK1MEN1KMT2ATHRB | |
| SCHEMBL29675212 | 0.69 | DRD2 (0.54) | HTR1AHTR7MEN1KMT2ADRD2 | |
| SCHEMBL28612645 | 0.69 | DRD2 (0.54) | HTR1AHTR7MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |