Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965674 | 0.89 | DRD2 (0.55) | DRD2MAPTALDH1A1LMNATHRB | |
| SCHEMBL30965568 | 0.88 | HTR4 (0.39) | DRD2HTR1AHTR2AGAADRD3 | |
| SCHEMBL30965765 | 0.87 | MAPT (0.44) | DRD2MAPTALDH1A1LMNAHTR1A | |
| SCHEMBL30965682 | 0.81 | CRBN (0.42) | DRD2 | |
| SCHEMBL30135712 | 0.80 | MAPT (0.45) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL29065775 | 0.78 | MAPT (0.47) | DRD2MAPTALDH1A1LMNATHRB | |
| SCHEMBL30965693 | 0.78 | HTR1A (0.44) | DRD2ALDH1A1HTR1AHTR2AGAA | |
| SCHEMBL30965749 | 0.78 | CHRM4 (0.50) | DRD2MAPTALDH1A1LMNAHTR1A | |
| SCHEMBL30965518 | 0.76 | DRD2 (0.47) | DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL29772039 | 0.76 | ALDH1A1 (0.54) | MAPTALDH1A1LMNATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |