Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.73 |
| ▸ | MMP2 | P08253 | 14/20 | 0.66 |
| ▸ | MMP9 | P14780 | 12/20 | 0.66 |
| ▸ | MMP3 | P08254 | 10/20 | 0.66 |
| ▸ | MMP13 | P45452 | 10/20 | 0.66 |
| ▸ | MMP1 | P03956 | 9/20 | 0.66 |
| ▸ | MMP7 | P09237 | 9/20 | 0.66 |
| ▸ | MMP14 | P50281 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099627 | 0.88 | ADAMTS4 (0.70) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL3094415 | 0.85 | ADAMTS4 (0.69) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL20124752 | 0.85 | ADAMTS4 (1.00) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL12730402 | 0.82 | ADAMTS4 (0.69) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL1658630 | 0.82 | ADAMTS4 (0.69) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL3099901 | 0.81 | MMP13 (0.64) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL4653257 | 0.80 | MMP2 (1.00) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL1750956 | 0.80 | MMP2 (1.00) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL32691806 | 0.80 | MMP2 (1.00) | ADAMTS4MMP2MMP9MMP3MMP13 | |
| SCHEMBL1655901 | 0.79 | ADAMTS4 (1.00) | ADAMTS4MMP2MMP9MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234307-A1 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-09-16 | — | — | US | claimed |
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BAYER HEALTHCARE LLC (US) | 2010-01-21 | — | — | US | claimed |
| US-20100234307-A1 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100234307-A1 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100234307-A1 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BAYER HEALTHCARE LLC (US) | 2010-01-21 | — | — | US | disclosed |
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BAYER HEALTHCARE LLC (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BCAT2, BCAT1, FABP4 | ADAMTS4 3197/4885MMP2 2401/4885MMP9 2453/4885 |
| US-20100234307-A1 | PREPARATION AND USE OF BIPHENYL AMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BCAT2, BCAT1, FABP4 | ADAMTS4 3197/4885MMP2 2401/4885MMP9 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.