Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729640 | 0.83 | L3MBTL1 (0.50) | NLRP3KAT6AL3MBTL1SLC40A1GLO1 | |
| SCHEMBL7959878 | 0.72 | L3MBTL1 (0.51) | NLRP3KAT6AL3MBTL1SLC40A1GLO1 | |
| SCHEMBL27771996 | 0.70 | L3MBTL1 (0.49) | NLRP3KAT6AL3MBTL1SLC40A1GLO1 | |
| SCHEMBL9370312 | 0.70 | L3MBTL1 (0.49) | NLRP3KAT6AL3MBTL1SLC40A1GLO1 | |
| SCHEMBL16549739 | 0.68 | PKM (0.55) | NLRP3KAT6AL3MBTL1SLC40A1GLO1 | |
| SCHEMBL25294544 | 0.66 | P4HTM (0.56) | NLRP3KAT6AL3MBTL1PTGS2NPC1 | |
| SCHEMBL18157894 | 0.66 | PTGS2 (0.71) | NLRP3L3MBTL1PTGS2METAP2NPC1 | |
| SCHEMBL136276 | 0.65 | MEN1 (0.40) | L3MBTL1MMP2PTGS2PKMPTGS1 | |
| SCHEMBL2059520 | 0.65 | MKNK1 (0.31) | — | |
| SCHEMBL10430944 | 0.65 | NLRP3 (0.47) | NLRP3KAT6AL3MBTL1SLC40A1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190992-A1 | Nicotinamide derivatives as synthesis units for producing agrochemical substances, and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100184973-A1 | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| CN-101687804-A | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG | 2010-03-31 | — | — | CN | disclosed |
| CN-101679398-A | Nicotinamide derivatives useful as synthetic units for the preparation of agricultural chemicals, and process for the preparation thereof | BAYER CROPSCIENCE AG | 2010-03-24 | — | — | CN | disclosed |
| EP-2160391-A1 | NICOTINAMIDE DERIVATIVES AS SYNTHESIS UNITS FOR PRODUCING AGROCHEMICAL SUBSTANCES, AND METHOD FOR THE PRODUCTION THEREOF | Bayer CropScience AG (DE) | 2010-03-10 | — | — | EP | disclosed |
| CN-101558036-A | Process for preparing 2-aminooxyethanol | BAYER CROPSCIENCE AG (DE) | 2009-10-14 | — | — | CN | disclosed |
| WO-2008155003-A1 | NICOTINAMIDE DERIVATIVES AS SYNTHESIS UNITS FOR PRODUCING AGROCHEMICAL SUBSTANCES, AND METHOD FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |
| EP-1728430-A1 | Herbicidal agents | Bayer CropScience GmbH (DE) | 2006-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190992-A1 | Nicotinamide derivatives as synthesis units for producing agrochemical substances, and method for the production thereof | NAMPT, NQO1, NNT | NLRP3 1255/4885KAT6A 4551/4885L3MBTL1 4513/4885 |
| US-20100184973-A1 | Method for producing dioxazine derivatives | CYP4Z1, CYP1A1, CYP2F1 | NLRP3 1724/4885KAT6A 3520/4885L3MBTL1 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.