Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989909 | 0.87 | CLK1 (0.48) | MEN1KMT2AROCK2ROCK1MAPK1 | |
| SCHEMBL30989970 | 0.82 | MAPT (0.44) | TSPOMEN1KMT2AROCK2ROCK1 | |
| SCHEMBL30989948 | 0.78 | TP53 (0.55) | KMT2AROCK2ROCK1MAPK1RIPK1 | |
| SCHEMBL30989952 | 0.78 | TP53 (0.55) | KMT2AROCK2ROCK1MAPK1RIPK1 | |
| SCHEMBL30989864 | 0.77 | CLK1 (0.51) | MEN1KMT2AALDH1A1RIPK1CLK1 | |
| SCHEMBL30989923 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HTTRIPK1 | |
| SCHEMBL30989886 | 0.76 | CLK1 (0.44) | RIPK1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL30989930 | 0.74 | HSP90AA1 (0.52) | MEN1KMT2AROCK2ROCK1ALDH1A1 | |
| SCHEMBL30989813 | 0.74 | CLK1 (0.43) | RIPK1CLK1CLK2DYRK1ACLK4 | |
| SCHEMBL30989898 | 0.73 | GPBAR1 (0.42) | MEN1KMT2AMAPK1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |