Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989832 | 0.82 | TSPO (0.43) | MAPTTP53TSPOROCK2ROCK1 | |
| SCHEMBL30989973 | 0.79 | RIPK1 (0.44) | MAPTALDH1A1MEN1KMT2AGPBAR1 | |
| SCHEMBL30989967 | 0.79 | RIPK1 (0.44) | MAPTALDH1A1MEN1KMT2AGPBAR1 | |
| SCHEMBL30989879 | 0.77 | LMNA (0.55) | MAPTROCK2ROCK1ALDH1A1MEN1 | |
| SCHEMBL30989786 | 0.77 | RXFP1 (0.45) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL30989882 | 0.76 | MEN1 (0.48) | MAPTROCK2ROCK1ALDH1A1KDM4E | |
| SCHEMBL30989921 | 0.75 | RIPK1 (0.45) | MAPTALDH1A1KDM4EL3MBTL1GPBAR1 | |
| SCHEMBL30989898 | 0.74 | GPBAR1 (0.42) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL30989930 | 0.73 | HSP90AA1 (0.52) | TP53ROCK2ROCK1ALDH1A1MEN1 | |
| SCHEMBL25228040 | 0.69 | GPBAR1 (0.43) | SMN1; SMN2MEN1KMT2AMAPK1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |