SCHEMBL117155

SCHEMBL117155

O=C(c1ccccc1)c1ccc(COc2cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c2OCc2ccc(C(=O)c3ccccc3)cc2)cc1.[Na+].[Na+]

nearest known ligand 0.52

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG known ✓ P37231 1/20 0.45
ATM Q13315 1/20 0.52
ALDH1A1 P00352 2/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SRD5A2 P31213 2/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
RXRA P19793 4/20 0.41
ADAMTS4 O75173 1/20 0.41
RXRB P28702 3/20 0.39
RXRG P48443 2/20 0.39
DUSP5 Q16690 1/20 0.39
HPGD P15428 1/20 0.39
PARP1 P09874 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29785771 1.00 ATM (0.52) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL2743027 0.84 ATM (0.51) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL3102000 0.83 ATM (0.50) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL10299029 0.81 ATM (0.51) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL1965566 0.80 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2MAPTRAB9AHPGD
SCHEMBL6659601 0.75 ATM (0.61) ATMALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL10448372 0.74 CA12 (0.48) ALDH1A1HTTSMN1; SMN2L3MBTL1GAA
SCHEMBL1964224 0.73 DUSP5 (0.50) MAPTDUSP5
SCHEMBL6664749 0.71 LMNA (0.63) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL9557135 0.71 CA2 (0.59) ATMALDH1A1L3MBTL1SRD5A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039087-B1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS HERAEUS MEDICAL COMPONENTS LLC (US) 2023-12-06 EP claimed
US-10800931-B2 Conductive polymeric coatings, medical devices, coating solutions and methods HERAEUS MEDICAL COMPONENTS LLC (US) 2020-10-13 US claimed
US-20170304506-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES BANK OF MONTREAL, AS COLLATERAL AGENT 2017-10-26 US claimed
US-20160208114-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS HERAEUS MEDICAL COMPONENTS LLC 2016-07-21 US claimed
EP-3039087-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS SurModics, Inc. (US) 2016-07-06 EP claimed
US-9375517-B2 Lubricious medical device coating with low particulates SURMODIES, INC. (US) 2016-06-28 US claimed
EP-2804915-B1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS INC (US) 2016-03-30 EP claimed
WO-2015031265-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS SURMODICS, INC. (US) 2015-03-05 WO claimed
EP-2804915-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SurModics, Inc. (US) 2014-11-26 EP claimed
US-20130197433-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS, INC. (US) 2013-08-01 US claimed
WO-2013109930-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS, INC. (US) 2013-07-25 WO claimed
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE SURMODICS INC (US) 2026-04-23 US disclosed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 US disclosed
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SURMODICS INC (US) 2026-04-09 US disclosed
US-12472288-B2 Lubricious coating for medical device SURMODICS, INC. (US) 2025-11-18 US disclosed
US-20130197433-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS, INC. (US) 2013-08-01 US disclosed
WO-2013109930-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS, INC. (US) 2013-07-25 WO disclosed
EP-2424581-A2 DEVICES AND METHODS FOR DELIVERY OF BIOACTIVE AGENTS SurModics, Inc. (US) 2012-03-07 EP disclosed
WO-2010129328-A2 DEVICES AND METHODS FOR DELIVERY OF BIOACTIVE AGENTS SURMODICS, INC. (US) 2010-11-11 WO disclosed
US-20100272774-A1 DEVICES AND METHODS FOR DELIVERY OF BIOACTIVE AGENTS SURMODICS, INC. (US) 2010-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE MUC1, ADH1A, PTK2 PPARG 3692/4885ATM 117/4885ALDH1A1 45/4885
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES CUTA, EED, SELP PPARG 2746/4885ATM 1064/4885ALDH1A1 135/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP PPARG 2702/4885ATM 67/4885ALDH1A1 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.