Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994734 | 0.87 | MTNR1A (0.51) | VNN1GPR119RIPK1CTSSCTSK | |
| SCHEMBL31552004 | 0.81 | RIPK1 (0.42) | GPR119RIPK1MTNR1AMTNR1B | |
| SCHEMBL15334186 | 0.80 | L3MBTL1 (0.52) | ALDH1A1TAAR1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL28301761 | 0.80 | MTNR1A (0.48) | GPR119MTNR1AMTNR1B | |
| SCHEMBL4664826 | 0.79 | VNN1 (0.60) | VNN1GPR119RIPK1CTSSCTSK | |
| SCHEMBL29059884 | 0.78 | CTSS (0.43) | RIPK1CTSSCTSKALDH1A1TAAR1 | |
| SCHEMBL5089657 | 0.78 | CA12 (0.47) | VNN1ALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL3456260 | 0.77 | RIPK1 (0.41) | VNN1GPR119RIPK1CTSSCTSK | |
| SCHEMBL2206253 | 0.77 | ALDH1A1 (0.48) | VNN1RIPK1ALDH1A1TAAR1SMN1; SMN2 | |
| SCHEMBL29181812 | 0.77 | MTNR1A (0.45) | MTNR1AMTNR1BRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024167922-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-08-15 | — | — | WO | disclosed |