Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.44 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 8/20 | 0.42 |
| ▸ | HRH1 | P35367 | 8/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057929 | 0.93 | SHMT1 (0.44) | GPR4ACKR3SHMT1HRH2HRH1 | |
| SCHEMBL31057864 | 0.90 | ACKR3 (0.49) | GPR4ACKR3SHMT1GPR119KDM4E | |
| SCHEMBL31057939 | 0.89 | SIGMAR1 (0.42) | GPR4ACKR3SHMT1CYP1A2CYP2C9 | |
| SCHEMBL31057868 | 0.88 | SIGMAR1 (0.43) | ACKR3SHMT1SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL31578853 | 0.87 | ACKR3 (0.48) | GPR4ACKR3HRH2HRH1CYP4F2 | |
| SCHEMBL31057883 | 0.86 | SIGMAR1 (0.45) | ACKR3SHMT1SIGMAR1DRD3 | |
| SCHEMBL31057975 | 0.84 | SHMT1 (0.42) | SHMT1SIGMAR1ALDH1A1DRD3 | |
| SCHEMBL31057873 | 0.81 | SIGMAR1 (0.43) | ACKR3SHMT1SIGMAR1ALDH1A1DRD3 | |
| SCHEMBL31578793 | 0.79 | ACKR3 (0.48) | GPR4ACKR3HRH2HRH1CYP4F2 | |
| SCHEMBL31578942 | 0.77 | ACKR3 (0.53) | GPR4ACKR3HRH2HRH1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173718-A2 | HETEROBIFUNCTIONAL BINDERS OF KLHDC2 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2024-08-22 | — | — | WO | disclosed |