Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 4/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19102582 | 0.98 | LMNA (0.51) | LMNAERAP1KDM4EALDH1A1MAPT | |
| Iodide SCHEMBL31058795 | 0.96 | LMNA (0.50) | LMNAERAP1KDM4EALDH1A1MAPT | |
| SCHEMBL5808604 | 0.81 | LMNA (0.50) | LMNAERAP1KDM4EALDH1A1MAPT | |
| Water SCHEMBL21823213 | 0.75 | ERAP1 (0.49) | LMNAERAP1KDM4EALDH1A1MAPT | |
| SCHEMBL14838062 | 0.73 | LMNA (0.55) | LMNAERAP1KDM4EALDH1A1MAPT | |
| SCHEMBL1049324 | 0.72 | ERAP1 (0.50) | LMNAERAP1KDM4EALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL10941568 | 0.72 | LMNA (0.54) | LMNAKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL15182269 | 0.72 | ERAP1 (0.46) | LMNAERAP1KDM4EALDH1A1MAPT | |
| SCHEMBL28960268 | 0.72 | LMNA (0.61) | LMNAERAP1KDM4EALDH1A1MAPT | |
| SCHEMBL7770227 | 0.71 | KDM4E (0.42) | LMNAERAP1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688657-A1 | EMM-75 MOLECULAR SIEVE COMPOSITIONS, SYNTHESES, AND USES | ExxonMobil Technology and Engineering Company (US) | 2026-02-11 | — | — | EP | disclosed |
| US-20240327231-A1 | EMM-75 MOLECULAR SIEVE COMPOSITIONS, SYNTHESES, AND USES | ExxonMobil Technology and Engineering Company | 2024-10-03 | — | — | US | disclosed |
| WO-2024206224-A1 | EMM-75 MOLECULAR SIEVE COMPOSITIONS, SYNTHESES, AND USES | ExxonMobil Technology and Engineering Company (US) | 2024-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327231-A1 | EMM-75 MOLECULAR SIEVE COMPOSITIONS, SYNTHESES, AND USES | MASP2, SRP72, CD74 | LMNA 2118/4885ERAP1 1242/4885KDM4E 3417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.