Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.70 |
| ▸ | TGM2 | P21980 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5122686 | 0.94 | TGM2 (0.67) | SIGMAR1TGM2TSHRALDH1A1GAA | |
| SCHEMBL5692127 | 0.86 | CTSL (0.67) | SIGMAR1TGM2TSHRALDH1A1GAA | |
| SCHEMBL7394267 | 0.83 | TSHR (0.62) | SIGMAR1TGM2TSHRALDH1A1GAA | |
| SCHEMBL30289263 | 0.83 | ALDH1A1 (0.61) | SIGMAR1TGM2TSHRALDH1A1GAA | |
| SCHEMBL10361893 | 0.83 | SIGMAR1 (0.65) | SIGMAR1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL30289124 | 0.83 | ALDH1A1 (0.64) | SIGMAR1TGM2TSHRALDH1A1GAA | |
| SCHEMBL6901870 | 0.81 | CTSL (0.57) | TGM2TSHRALDH1A1GAACTSL | |
| SCHEMBL20640315 | 0.81 | SIGMAR1 (0.73) | SIGMAR1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL1870659 | 0.81 | TGM2 (0.72) | TGM2TSHRALDH1A1GAACTSL | |
| SCHEMBL381922 | 0.80 | ALDH1A1 (0.85) | TSHRALDH1A1GAACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131843-A1 | ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 苏州宜联生物医药有限公司 | 2024-06-27 | — | — | WO | disclosed |