SCHEMBL31073142

SCHEMBL31073142

CC(C)(C)[Si](C)(C)OCc1ccc(N2C3CCC2CN(c2ccc(N)nc2)C3)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
GPR119 Q8TDV5 2/20 0.32
TRPC6 Q9Y210 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31073262 0.82 HRH3 (0.36) GPR119
SCHEMBL31073153 0.81 DHFR (0.34) GPR119TRPC6
SCHEMBL31073273 0.80 USP14 (0.33) GPR119
SCHEMBL31072986 0.79 KCNH2 (0.41)
SCHEMBL31073006 0.79 HRH3 (0.38)
SCHEMBL31073126 0.78 CHRNB2 (0.39) CHRNB2CHRNA4TRPC6
SCHEMBL31073086 0.77 TRPC6 (0.36) TRPC6
SCHEMBL31073002 0.77 GCK (0.38) GPR119TRPC6
SCHEMBL31073107 0.76 USP14 (0.33) TRPC6
SCHEMBL31073352 0.75 TRPC6 (0.39) TRPC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173646-A1 CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-08-22 WO disclosed