Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TNKS | O95271 | 4/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.44 |
| ▸ | ME2 | P23368 | 1/20 | 0.44 |
| ▸ | ME1 | P48163 | 1/20 | 0.44 |
| ▸ | ME3 | Q16798 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CLPP | Q16740 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087174 | 0.75 | SPR (0.52) | ALDH1A1MAPTPARP1EHMT2 | |
| SCHEMBL17252127 | 0.74 | TNKS (0.65) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL10305162 | 0.73 | FKBP1A (0.76) | ALDH1A1TSHRKMT2AMAPTFKBP1A | |
| SCHEMBL21064517 | 0.72 | GPBAR1 (0.53) | ALDH1A1TSHRKMT2AMAPTTNKS | |
| SCHEMBL2833225 | 0.71 | KMT2A (0.80) | ALDH1A1TSHRKMT2AMAPTFKBP1A | |
| SCHEMBL20989035 | 0.71 | FKBP1A (0.59) | ALDH1A1TSHRKMT2AMAPTFKBP1A | |
| SCHEMBL4383272 | 0.69 | ALDH1A1 (0.98) | ALDH1A1TSHRKMT2AFKBP1AME2 | |
| SCHEMBL4384079 | 0.68 | ALDH1A1 (1.00) | ALDH1A1TSHRKMT2AFKBP1AME2 | |
| SCHEMBL31087187 | 0.67 | MAPT (0.56) | ALDH1A1TSHRMAPTSMN1; SMN2EHMT2 | |
| SCHEMBL14218027 | 0.66 | FKBP1A (0.69) | ALDH1A1TSHRKMT2AMAPTFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240307394-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | INCYTE CORPORATION | 2024-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240307394-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | MRGPRX1, MRGPRX4, MRGPRX2 | ALDH1A1 3659/4885TSHR 120/4885KMT2A 4353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.