Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984884 | 0.78 | ENO1 (0.37) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL9681566 | 0.76 | FAAH (0.62) | KMT2A | |
| Phosphoric Acid SCHEMBL10889003 | 0.76 | CNR1 (0.46) | BLMKMT2ACA1CA2SLC6A5 | |
| SCHEMBL3090756 | 0.76 | TSHR (0.37) | TSHRCYP1A2KMT2ACA1CA2 | |
| Phosphoric Acid SCHEMBL11427044 | 0.75 | CNR1 (0.43) | TSHRCA1CA2SLC6A5 | |
| SCHEMBL3029084 | 0.74 | CYP1A2 (0.42) | TSHRCYP1A2KMT2ACA1CA2 | |
| SCHEMBL10819092 | 0.74 | CASP2 (0.47) | LMNACYP3A4HDAC3HDAC1HDAC2 | |
| SCHEMBL4633674 | 0.73 | LMNA (0.41) | LMNABLMCYP3A4NFKB1PMP22 | |
| Hydrochloric Acid SCHEMBL3029081 | 0.73 | CYP1A2 (0.41) | TSHRCYP1A2CA1CA2SLC6A5 | |
| SCHEMBL28920865 | 0.73 | LPAR1 (0.50) | LMNABLMCYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |