SCHEMBL31093171

SCHEMBL31093171

O=C(CCN1CCc2ccccc2C1)c1ccccc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 7/20 0.84
DRD2 P14416 7/20 0.84
HTR7 P34969 7/20 0.84
DRD3 P35462 7/20 0.84
HTR2B P41595 7/20 0.84
HTR2A P28223 6/20 0.84
HRH1 P35367 6/20 0.84
SLC6A4 P31645 3/20 0.84
PRMT5 O14744 2/20 0.67
WDR77 Q9BQA1 2/20 0.67
HDAC3 O15379 1/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
NCOR2 Q9Y618 1/20 0.65
KDM4E B2RXH2 1/20 0.64
ALOX15 P16050 1/20 0.64
ALDH1A1 P00352 5/20 0.64
LMNA P02545 1/20 0.64
TP53 P04637 1/20 0.64
HPGD P15428 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20358752 0.91 HTR1A (1.00) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL3477555 0.86 HDAC3 (0.70) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL12123654 0.84 ALDH1A1 (0.66) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL20364974 0.82 DRD2 (1.00) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL10623034 0.82 DRD3 (0.59) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL31093087 0.82 HTR1A (0.62) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL3891857 0.81 HDAC3 (0.68) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL7647981 0.81 HTR1A (1.00) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL20358377 0.81 HTR1A (1.00) HTR1ADRD2HTR7DRD3HTR2B
SCHEMBL7647706 0.81 HTR1A (0.81) HTR1ADRD2HTR7DRD3HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME INFINEUM INTERNATIONAL LIMITED (GB) 2024-08-29 US disclosed
EP-4410772-A2 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME Infineum International Limited (GB) 2024-08-07 EP disclosed
CN-118440229-A Amine functional monomers and methods of making the same 英菲诺姆国际有限公司 2024-08-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME AMD1, HNMT, MAT1A HTR1A 857/4885DRD2 1292/4885HTR7 1751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.