Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28920891 | 0.87 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9ANPBWR1HSD11B1 | |
| SCHEMBL21835458 | 0.76 | HSD11B1 (0.38) | SMN1; SMN2NPC1RAB9ANPBWR1HSD11B1 | |
| SCHEMBL29383185 | 0.76 | HSD11B1 (0.38) | SMN1; SMN2NPC1RAB9ANPBWR1HSD11B1 | |
| SCHEMBL21835475 | 0.74 | MAPT (0.45) | SMN1; SMN2NPC1RAB9ANPBWR1HSD11B1 | |
| SCHEMBL29384915 | 0.74 | MAPT (0.45) | SMN1; SMN2NPC1RAB9ANPBWR1HSD11B1 | |
| SCHEMBL25202984 | 0.74 | HPGD (0.38) | SMN1; SMN2NPC1RAB9AHSD11B1MAPT | |
| SCHEMBL28612147 | 0.73 | ALDH1A1 (0.39) | SMN1; SMN2NPC1RAB9ANPBWR1MAPT | |
| SCHEMBL21835554 | 0.72 | RAB9A (0.41) | SMN1; SMN2NPC1RAB9ANPBWR1HSD11B1 | |
| SCHEMBL21835495 | 0.72 | NPBWR1 (0.41) | SMN1; SMN2NPC1RAB9ANPBWR1HSD11B1 | |
| SCHEMBL29383170 | 0.72 | RAB9A (0.41) | SMN1; SMN2NPC1RAB9ANPBWR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039233-A | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118994028-A | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-113166075-B | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-10-25 | — | — | CN | disclosed |