Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | KDM5A | P29375 | 1/20 | 0.64 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.64 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.59 |
| ▸ | TNKS | O95271 | 5/20 | 0.59 |
| ▸ | WNT3A | P56704 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 3/20 | 0.56 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30388114 | 1.00 | PKM (1.00) | PKMKDM5AKDM4CHCAR2TNKS2 | |
| SCHEMBL7533742 | 0.84 | PKM (0.72) | PKMTNKS2TNKSWNT3APARP1 | |
| SCHEMBL11800814 | 0.83 | PKM (0.71) | PKMKDM5AKDM4CTNKS2TNKS | |
| SCHEMBL894415 | 0.82 | PKM (0.70) | PKMTNKS2TNKSWNT3APARP1 | |
| SCHEMBL10779491 | 0.82 | PKM (0.70) | PKMTNKS2TNKSNPSR1PARP1 | |
| SCHEMBL29179948 | 0.79 | PKM (0.66) | PKMTNKS2TNKSPARP1QTRT1 | |
| SCHEMBL7530802 | 0.79 | PKM (0.66) | PKMTNKS2TNKSWNT3APARP1 | |
| SCHEMBL23066107 | 0.78 | PKM (0.64) | PKMKDM5AKDM4CHCAR2TNKS2 | |
| SCHEMBL31279924 | 0.78 | KDM4C (1.00) | PKMKDM5AKDM4CHCAR2MAPT | |
| SCHEMBL3958548 | 0.78 | KDM4C (0.77) | PKMKDM5AKDM4CHCAR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021033141-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2021-02-25 | — | — | WO | claimed |
| WO-2017187324-A1 | SUBSTITUTED FUSED PYRIMIDINONE COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2017-11-02 | — | — | WO | claimed |
| WO-2014128612-A1 | QUINAZOLIN-4-ONE DERIVATIVES | NOVARTIS AG (CH) | 2014-08-28 | — | — | WO | claimed |
| EP-1071426-A2 | NOVEL COMPOUNDS AND THEIR USE AS POSITIVE AMPA RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2001-01-31 | — | — | EP | claimed |
| WO-1999042456-A2 | NOVEL COMPOUNDS AND THEIR USE AS POSITIVE AMPA RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 1999-08-26 | — | — | WO | claimed |
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| WO-2021033141-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2021-02-25 | — | — | WO | disclosed |
| EP-3154961-A1 | QUINAZOLINONE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | disclosed |
| CN-105829285-A | Quinazolinone and isoquinolinone derivatives | 中外制药株式会社 | 2016-08-03 | — | — | CN | disclosed |
| WO-2015191743-A1 | QUINAZOLINONE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | disclosed |
| US-20140364420-A1 | SUBSTITUTED PIPERAZINYL-PYRROLIDINE COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-12-11 | — | — | US | disclosed |
| US-5284739-A | Devloper and coupler present in drops of a high-boiling solvent; water pollution control | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| US-5256781-A | Anticholesterol, antilipemic, hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0565165-A1 | Photographic silver halide colour materials | KODAK LIMITED (GB) | 1993-10-13 | — | — | EP | disclosed |
| US-5236925-A | Hypotensive agents, treatment of congestive heart failure | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0545491-A1 | Photographic silver halide colour materials | KODAK LIMITED (GB) | 1993-06-09 | — | — | EP | disclosed |
| WO-1993008170-A1 | SUBSTITUTED HETEROCYCLES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-29 | — | — | WO | disclosed |
| US-5187168-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |
| US-3962444-A | Use of 4-thiocyano-quinazolines as fungicides | U.S. PHILIPS CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | AHR, ARNT, MTNR1A | PKM 3804/4885KDM5A 3944/4885KDM4C 4431/4885 |
| US-20140364420-A1 | SUBSTITUTED PIPERAZINYL-PYRROLIDINE COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | ACKR3, CCR5, CCR2 | PKM 1914/4885KDM5A 2859/4885KDM4C 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.