Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.32 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185051 | 0.88 | DGAT1 (0.31) | — | |
| SCHEMBL31184615 | 0.80 | LMNA (0.31) | — | |
| SCHEMBL31184614 | 0.80 | ALDH1A1 (0.40) | TYK2ALDH1A1HPGD | |
| SCHEMBL31184524 | 0.80 | CHKA (0.34) | MAP3K5ALDH1A1 | |
| SCHEMBL31184568 | 0.79 | MAPK1 (0.32) | ALDH1A1 | |
| SCHEMBL31184992 | 0.79 | MGLL (0.41) | MCHR1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31184642 | 0.79 | ALDH1A1 (0.40) | TYK2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31184750 | 0.79 | BTK (0.34) | ALDH1A1 | |
| SCHEMBL31184822 | 0.78 | CYP1A2 (0.42) | ABL1ALDH1A1 | |
| SCHEMBL31185053 | 0.78 | TP53 (0.40) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |