Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184544 | 0.81 | HTR2C (0.36) | LMNAKMT2ATP53 | |
| SCHEMBL31184524 | 0.81 | CHKA (0.34) | CHKAALDH1A1LMNANPC1RAB9A | |
| SCHEMBL31184615 | 0.80 | LMNA (0.31) | LMNAMAPK1 | |
| SCHEMBL31184614 | 0.79 | ALDH1A1 (0.40) | CYP1A2CYP2C19CHKACHKBALDH1A1 | |
| SCHEMBL31184568 | 0.79 | MAPK1 (0.32) | ALDH1A1MAPK1 | |
| SCHEMBL31184642 | 0.79 | ALDH1A1 (0.40) | CYP1A2CYP2C19CHKACHKBALDH1A1 | |
| SCHEMBL31184992 | 0.79 | MGLL (0.41) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL31184403 | 0.78 | TYK2 (0.32) | ABL1ALDH1A1 | |
| SCHEMBL31184750 | 0.78 | BTK (0.34) | ALDH1A1RAB9A | |
| SCHEMBL31185053 | 0.77 | TP53 (0.40) | CYP1A2CYP2C19CHKACHKBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |