Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184574 | 0.87 | ACE (0.37) | CHRM4CHRM1ACEMMP13CDK5 | |
| SCHEMBL31184907 | 0.87 | JAK2 (0.40) | CHRM4CHRM1ACEMMP13CDK5 | |
| SCHEMBL31184661 | 0.82 | ALDH1A1 (0.34) | ALDH1A1BTKKDM4EGLAPKM | |
| SCHEMBL31184632 | 0.81 | MAPK1 (0.46) | ALDH1A1BTKALOX15RAB9AMAPT | |
| SCHEMBL31185102 | 0.80 | POLB (0.44) | ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL31184406 | 0.80 | POLB (0.43) | ALDH1A1HPGDSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL31184724 | 0.78 | TP53 (0.43) | ALDH1A1HPGDRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL31184736 | 0.78 | CDK5 (0.36) | CHRM4CHRM1CDK5CDK5R1RAMP1 | |
| SCHEMBL31184910 | 0.77 | TRPV1 (0.40) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31184511 | 0.76 | BRD4 (0.41) | CHRM4CHRM1CDK5CDK5R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |