Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184907 | 0.81 | JAK2 (0.40) | JAK2MEN1KMT2ATNKS | |
| SCHEMBL31184557 | 0.78 | JAK2 (0.36) | JAK2MEN1KMT2ASMN1; SMN2TNKS | |
| SCHEMBL31184492 | 0.78 | CHKA (0.42) | KMT2APOLBSMN1; SMN2HPGD | |
| SCHEMBL31184541 | 0.77 | JAK2 (0.38) | JAK2 | |
| SCHEMBL31184661 | 0.74 | ALDH1A1 (0.34) | JAK2KDM1ASMN1; SMN2KDM4E | |
| SCHEMBL31184494 | 0.68 | KDM1A (0.39) | KDM1ACA12CA1CA2CA4 | |
| SCHEMBL31184698 | 0.68 | CHRM4 (0.36) | JAK2MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL31184529 | 0.65 | MAPK1 (0.49) | MEN1KMT2ADUSP3 | |
| SCHEMBL31184736 | 0.64 | CDK5 (0.36) | — | |
| SCHEMBL12992123 | 0.62 | GRIA1 (0.41) | POLBCA9HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |