Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 3/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | HCK | P08631 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184798 | 0.85 | LCK (0.39) | LCKMAPK13EGFRFYNHCK | |
| SCHEMBL31184819 | 0.84 | NPC1 (0.49) | SMN1; SMN2RAB9ALCKALDH1A1NPC1 | |
| SCHEMBL31184673 | 0.81 | MALT1 (0.43) | RAB9ACHKANPC1PKMMEN1 | |
| SCHEMBL31185026 | 0.80 | KMT2A (0.48) | SMN1; SMN2RAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL31184691 | 0.79 | JAK2 (0.45) | SMN1; SMN2RAB9ACHKANPC1PKM | |
| SCHEMBL31184979 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2RAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL31184630 | 0.78 | HPGD (0.44) | SMN1; SMN2RAB9ANPC1MAPK1 | |
| SCHEMBL31184529 | 0.77 | MAPK1 (0.49) | MEN1KMT2AMAPK1 | |
| SCHEMBL31184632 | 0.77 | MAPK1 (0.46) | RAB9AALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL31184452 | 0.76 | MAPK1 (0.51) | ALDH1A1MEN1POLBKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |