Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216281 | 0.84 | APP (0.36) | MAOAMAOBAPPALDH1A1MAPT | |
| SCHEMBL10305087 | 0.84 | APP (0.36) | MAOAMAOBAPPALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3118484 | 0.82 | KCNH2 (0.36) | MAOAMAOBAPPALDH1A1MAPT | |
| SCHEMBL16216217 | 0.82 | APP (0.36) | MAOAMAOBAPPALDH1A1MAPT | |
| Formic Acid SCHEMBL29958453 | 0.77 | ALDH1A1 (0.36) | MAOAMAOBAPPALDH1A1MAPT | |
| SCHEMBL16216294 | 0.73 | APP (0.36) | APPALDH1A1MAPTLMNAKCNH2 | |
| SCHEMBL24240106 | 0.73 | APP (0.37) | MAOAMAOBAPPALDH1A1MAPT | |
| SCHEMBL20852480 | 0.69 | MAPT (0.35) | MAOAMAOBALDH1A1MAPTLMNA | |
| SCHEMBL21556950 | 0.69 | MAOA (0.49) | MAOAMAOBALDH1A1MAPTLMNA | |
| SCHEMBL19361310 | 0.69 | ALDH1A1 (0.51) | MAOAMAOBALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12324845-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2025-06-10 | — | — | US | disclosed |
| US-20250161500-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2025-05-22 | — | — | US | disclosed |
| US-20220288243-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-09-15 | — | — | US | disclosed |
| US-11241509-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| EP-2474525-B1 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING INC (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-2474523-B1 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING INC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-20180339070-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-11-29 | — | — | US | disclosed |
| US-10010631-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20140030189-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2014-01-30 | — | — | US | disclosed |
| US-8491868-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| EP-2114873-B1 | N-[3-BROMO-4-(3- [18F]FLUOROPROPOXY)-BENZYL]-GUANIDINE FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING INC (US) | 2013-02-20 | — | — | EP | disclosed |
| EP-2474523-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474525-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474526-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474524-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2010-09-02 | — | — | US | disclosed |
| EP-2114873-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | Lantheus Medical Imaging, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010631-B2 | Ligands for imaging cardiac innervation | TNNT2, PNMT, TNNC1 | MAOA 692/4885MAOB 543/4885APP 2683/4885 |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | MAOA 692/4885MAOB 543/4885APP 2683/4885 |
| US-20180339070-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | MAOA 692/4885MAOB 543/4885APP 2683/4885 |
| US-20220288243-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | MAOA 692/4885MAOB 543/4885APP 2683/4885 |
| US-11241509-B2 | Ligands for imaging cardiac innervation | TNNT2, PNMT, TNNC1 | MAOA 694/4885MAOB 530/4885APP 2703/4885 |
| US-20140030189-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | MAOA 692/4885MAOB 543/4885APP 2683/4885 |
| US-20250161500-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | MAOA 692/4885MAOB 543/4885APP 2683/4885 |
| US-12324845-B2 | Ligands for imaging cardiac innervation | CHRNB4, RXFP4, RXFP3 | MAOA 2610/4885MAOB 1919/4885APP 3739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.