Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.66 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | TNKS | O95271 | 3/20 | 0.66 |
| ▸ | PARP1 | P09874 | 3/20 | 0.66 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.66 |
| ▸ | DHODH | Q02127 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311705 | 0.89 | POLH (0.66) | POLHCYP3A4MAPTALOX5KDM4E | |
| SCHEMBL311162 | 0.86 | MAPT (0.66) | POLHCYP3A4MAPTKDM4EALOX15 | |
| SCHEMBL345706 | 0.80 | TNKS (1.00) | POLHCYP3A4MAPTALOX5KDM4E | |
| SCHEMBL29664745 | 0.80 | TNKS (1.00) | POLHCYP3A4MAPTALOX5KDM4E | |
| SCHEMBL2218499 | 0.79 | POLH (0.75) | POLHCYP3A4MAPTALOX5KDM4E | |
| SCHEMBL29664594 | 0.78 | ALOX5 (0.78) | POLHCYP3A4MAPTALOX5KDM4E | |
| SCHEMBL491032 | 0.78 | ALOX5 (0.78) | POLHCYP3A4MAPTALOX5KDM4E | |
| SCHEMBL30591365 | 0.78 | ALOX5 (0.78) | POLHCYP3A4MAPTALOX5KDM4E | |
| SCHEMBL313278 | 0.78 | HPGD (0.66) | POLHCYP3A4MAPTALOX5KDM4E | |
| SCHEMBL312700 | 0.77 | POLH (0.53) | POLHCYP3A4MAPTALOX5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242130-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-08-14 | — | — | US | disclosed |
| EP-1838296-B1 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP (CA) | 2012-08-08 | — | — | EP | disclosed |
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |
| US-20090259048-A1 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. (CA) | 2009-10-15 | — | — | US | disclosed |
| US-20060205767-A1 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | HEPALINK (HONG KONG) LIMITED (HK) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205767-A1 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | APOB, APOL1, FABP3 | POLH 4318/4885CYP3A4 1730/4885MAPT 2914/4885 |
| US-20090259048-A1 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | APOB, APOL1, FABP3 | POLH 4318/4885CYP3A4 1730/4885MAPT 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.