Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145378 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL5648168 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL25378343 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL639750 | 0.97 | TSHR (0.42) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL318154 | 0.89 | TSHR (0.41) | TSHRTHRBDNM1LMNA | |
| SCHEMBL8318187 | 0.82 | DNM1 (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL317337 | 0.82 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL8321451 | 0.82 | DNM1 (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL1405657 | 0.82 | DNM1 (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL5958083 | 0.82 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355794-A1 | FREE-RADICALLY POLYMERIZABLE COPOLYMER, FREE-RADICALLY POLYMERIZABLE COMPOSITION CONTAINING THE SAME, AND POLYMERIZED REACTION PRODUCT THEREFROM | 3M Innovative Properties Company (US) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263987-A1 | FREE-RADICALLY POLYMERIZABLE COPOLYMER, FREE-RADICALLY POLYMERIZABLE COMPOSITION CONTAINING THE SAME, AND POLYMERIZED REACTION PRODUCT THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-12-22 | — | — | WO | disclosed |
| EP-2016939-B1 | TRANSDERMALLY ABSORBABLE PREPARATION COMPRISING ANTI-DEMENTIA AGENT | TEIKOKU SEIYAKU KK (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-20110059141-A1 | PERCUTANEOUS ABSORPTION PREPARATIONS OF ANTIDEMENTIA DRUGS | ITO TAKESHI | 2011-03-10 | — | — | US | disclosed |
| US-7858114-B2 | used as plaster on skin; comprises adherent layer, intermediate membrane, and drug reservoir layer sequentially from skin side, wherein drug reservoir layer comprises an antidementia drug, an aminated polymer, a polyhydric alcohol, and carboxylic acid esters | TEIKOKU SEIYAKU CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20100178307-A1 | TRANSDERMAL ANTI-DEMENTIA ACTIVE AGENT FORMULATIONS AND METHODS FOR USING THE SAME | TEIKOKU PHARMA USA INC. | 2010-07-15 | — | — | US | disclosed |
| EP-2016939-A1 | TRANSDERMALLY ABSORBABLE PREPARATION COMPRISING ANTI-DEMENTIA AGENT | TEIKOKU SEIYAKU CO., LTD. (JP) | 2009-01-21 | — | — | EP | disclosed |
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-20070259028-A1 | used as plaster on skin; comprises adherent layer, intermediate membrane, and drug reservoir layer sequentially from skin side, wherein drug reservoir layer comprises an antidementia drug, an aminated polymer, a polyhydric alcohol, and carboxylic acid esters | TEIKOKU SEIYAKU CO., LTD. (JP) | 2007-11-08 | — | — | US | disclosed |
| US-7276600-B2 | Phthalocyanine derivatives and their applications in optical recording media | TSAI YEN CHENG | 2007-10-02 | — | — | US | disclosed |
| US-20060292494-A1 | Novel phthalocyanine derivatives, synthetic process thereof and their applications in optical recording media | TSAI YEN C | 2006-12-28 | — | — | US | disclosed |
| US-20060281026-A1 | Phthalocyanine derivatives and their applications in optical recording media | TSAI YEN C | 2006-12-14 | — | — | US | disclosed |
| US-20050085642-A1 | Novel bipyridine derivatives | SANKIO CHEMICAL CO., LTD. | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085642-A1 | Novel bipyridine derivatives | PFAS, CBR3, Q6ZSR9 | TSHR 726/4885THRB 1975/4885FAAH 4059/4885 |
| US-20060292494-A1 | Novel phthalocyanine derivatives, synthetic process thereof and their applications in optical recording media | TRPC3, TRPA1, TRPC6 | TSHR 2593/4885THRB 1173/4885FAAH 4818/4885 |
| US-20060281026-A1 | Phthalocyanine derivatives and their applications in optical recording media | CRY2, CACNA1C, CRY1 | TSHR 3982/4885THRB 2759/4885FAAH 3539/4885 |
| US-20100178307-A1 | TRANSDERMAL ANTI-DEMENTIA ACTIVE AGENT FORMULATIONS AND METHODS FOR USING THE SAME | ACHE, CHAT, GAP43 | TSHR 4744/4885THRB 4117/4885FAAH 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.