Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | CLK2 | P49760 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240391 | 0.85 | DYRK1A (0.42) | DYRK1ACLK2TBK1CLK3CCNT1 | |
| SCHEMBL31240455 | 0.82 | TGFBR1 (0.39) | DYRK1ACLK2AURKAEGFRCLK3 | |
| SCHEMBL31240393 | 0.81 | CCNT1 (0.38) | ROCK2DYRK1ACLK2AURKAPRKACA | |
| SCHEMBL31240766 | 0.79 | AURKA (0.47) | DYRK1ACLK2AURKATBK1EGFR | |
| SCHEMBL31240548 | 0.77 | TBK1 (0.46) | DYRK1ACDK1CDK2TBK1CDK9 | |
| SCHEMBL31240449 | 0.77 | CCNT1 (0.39) | ROCK2DYRK1ACLK2AURKAPRKACA | |
| SCHEMBL31240258 | 0.75 | DYRK1A (0.44) | DYRK1ACLK2TBK1CLK3 | |
| SCHEMBL31240575 | 0.74 | MAP3K11 (0.41) | ROCK2ROCK1CDC42BPBDYRK1ACLK2 | |
| SCHEMBL31240648 | 0.69 | TRPA1 (0.41) | DYRK1ACLK2CDK2GSK3BCDK5 | |
| SCHEMBL26686672 | 0.69 | DYRK1A (0.42) | DYRK1ACLK2GSK3BTNIKCLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |