SCHEMBL3133121

SCHEMBL3133121

CC(C)(C)N(CC(N)=S)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17641539 0.82 MEN1 (0.34) MEN1KMT2AHTTL3MBTL1
SCHEMBL5946036 0.75 CYP2D6 (0.32) MEN1KMT2AHTTL3MBTL1
SCHEMBL2237272 0.72 KDM4E (0.37) MEN1KMT2AHTTL3MBTL1
SCHEMBL2499845 0.71 MEN1 (0.37) MEN1KMT2AHTTL3MBTL1
SCHEMBL2347582 0.70
Carbamic Acid SCHEMBL30900855 0.70 MEN1 (0.33) MEN1KMT2AHTTL3MBTL1
SCHEMBL968381 0.69 MEN1 (0.37) MEN1KMT2AHTTL3MBTL1
SCHEMBL17093961 0.69 TMEM97 (0.32) MEN1KMT2A
SCHEMBL246225 0.68 MEN1 (0.34) MEN1KMT2AHTTL3MBTL1
SCHEMBL6228764 0.68 MEN1 (0.34) MEN1KMT2AHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286411-B2 Indane derivatives for use in the treatment of bacterial infection ANTABIO SAS (FR) 2025-04-29 US disclosed
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed
US-20240016941-A1 COMBINATION THERAPY ANTABIO SAS (FR) 2024-01-18 US disclosed
EP-3601224-B1 CHEMICAL COMPOUNDS AS ANTIBIOTICS ANTABIO SAS (FR) 2023-07-05 EP disclosed
EP-4125883-A1 COMBINATION THERAPY Antabio SAS (FR) 2023-02-08 EP disclosed
US-20210347748-A1 INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION ANTABIO SAS (FR) 2021-11-11 US disclosed
WO-2021191240-A1 COMBINATION THERAPY ANTABIO SAS (FR) 2021-09-30 WO disclosed
EP-3856729-A1 INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION Antabio SAS (FR) 2021-08-04 EP disclosed
EP-3027615-B1 ANTI-INFECTIVE COMPOUNDS PASTEUR INSTITUT KOREA (KR) 2021-07-21 EP disclosed
US-11000511-B2 Chemical compounds as antibiotics ANTABIO SAS (FR) 2021-05-11 US disclosed
US-20200155509-A1 CHEMICAL COMPOUNDS AS ANTIBIOTICS ANTABIO SAS (FR) 2020-05-21 US disclosed
WO-2020064173-A1 INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION ANTABIO SAS (FR) 2020-04-02 WO disclosed
EP-3628666-A1 INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION Antabio SAS (FR) 2020-04-01 EP disclosed
EP-3601224-A1 CHEMICAL COMPOUNDS AS ANTIBIOTICS Antabio SAS (FR) 2020-02-05 EP disclosed
WO-2018172423-A1 CHEMICAL COMPOUNDS AS ANTIBIOTICS ANTABIO SAS (FR) 2018-09-27 WO disclosed
US-20160185774-A1 Anti-Infective Compounds INSTITUT PASTEUR KOREA (KR) 2016-06-30 US disclosed
EP-3027615-A2 ANTI-INFECTIVE COMPOUNDS Institut Pasteur Korea (KR) 2016-06-08 EP disclosed
WO-2015014993-A2 ANTI-INFECTIVE COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2015-02-05 WO disclosed
WO-2010001220-A1 NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF MUTABILIS SA (FR) 2010-01-07 WO disclosed
EP-2141164-A1 New 1,2,4-triazine derivatives and biological applications thereof Mutabilis (FR) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12286411-B2 Indane derivatives for use in the treatment of bacterial infection ELANE, ARG1, INSRR MEN1 1135/4885KMT2A 3671/4885HTT 4559/4885
US-20200155509-A1 CHEMICAL COMPOUNDS AS ANTIBIOTICS MRPL21, CFTR, H1-0 MEN1 569/4885KMT2A 825/4885HTT 4197/4885
US-20240016941-A1 COMBINATION THERAPY CFTR, ABCB11, SLC26A4 MEN1 2052/4885KMT2A 2615/4885HTT 3701/4885
US-20160185774-A1 Anti-Infective Compounds RABGGTB, ELANE, SERPINB1 MEN1 3685/4885KMT2A 4781/4885HTT 3860/4885
US-11000511-B2 Chemical compounds as antibiotics MRPL21, CFTR, H1-0 MEN1 569/4885KMT2A 825/4885HTT 4197/4885
US-20210347748-A1 INDANE DERIVATIVES FOR USE IN THE TREATMENT OF BACTERIAL INFECTION INSR, INSRR, ARG1 MEN1 1447/4885KMT2A 3696/4885HTT 4599/4885
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD MEN1 4188/4885KMT2A 1791/4885HTT 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.