Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ADA | P00813 | 4/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333037 | 0.85 | SMN1; SMN2 (0.51) | CYP2C19KMT2ALMNA | |
| SCHEMBL31333075 | 0.85 | MAPT (0.45) | LMNAKDM4EMKNK1MKNK2 | |
| SCHEMBL31333059 | 0.82 | PDE5A (0.47) | KMT2ALMNA | |
| SCHEMBL31333054 | 0.82 | ALDH1A1 (0.47) | SIRT2SIRT1KDM4EMKNK1MKNK2 | |
| SCHEMBL31333089 | 0.78 | ADRA1D (0.51) | KMT2ASIRT1LMNAKDM4E | |
| SCHEMBL31333083 | 0.76 | PPARG (0.40) | KDM4ESLC29A1 | |
| SCHEMBL31333082 | 0.76 | ROCK2 (0.39) | SLC29A1 | |
| SCHEMBL31333084 | 0.75 | CA5A (0.52) | — | |
| SCHEMBL31333071 | 0.74 | CCNC (0.45) | KMT2AKDM4EL3MBTL1MKNK1MKNK2 | |
| SCHEMBL31333078 | 0.73 | GRM2 (0.47) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |