Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333017 | 0.84 | TP53 (0.45) | NAMPTMMP13L3MBTL1HPGDMEN1 | |
| SCHEMBL31333078 | 0.84 | GRM2 (0.47) | MMP13KDM4EHPGD | |
| SCHEMBL31333091 | 0.83 | ADRA1D (0.51) | CNOT7MMP13KDM4EHSD17B10L3MBTL1 | |
| SCHEMBL16861414 | 0.81 | MEN1 (0.48) | MMP13KDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL31333055 | 0.81 | MMP13 (0.41) | MMP13 | |
| SCHEMBL31333022 | 0.78 | ROCK2 (0.44) | MMP13ALDH1A1HSD17B13KDM4CMKNK1 | |
| SCHEMBL31333025 | 0.78 | ALDH1A1 (0.51) | MMP13KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL31333089 | 0.77 | ADRA1D (0.51) | CNOT7KDM4EHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL31333065 | 0.74 | CYP2C19 (0.40) | KDM4EL3MBTL1KMT2AMKNK1MKNK2 | |
| SCHEMBL31333084 | 0.74 | CA5A (0.52) | KDM4CMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |