SCHEMBL31339943

SCHEMBL31339943

Cc1cnc(NC(=O)c2ccc(C(F)(F)F)cc2)nc1-c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 2/20 0.48
▸ STAT3 P40763 1/20 0.47
▸ MAPT P10636 6/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ LMNA P02545 2/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ RECQL P46063 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ THRB P10828 1/20 0.47
▸ NPC1 O15118 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ SORT1 Q99523 1/20 0.44
▸ HPGD P15428 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31339981 0.92 ALDH1A1 (0.43) TRPV1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL31339975 0.89 TRPV1 (0.53) TRPV1MAPTALDH1A1
SCHEMBL31340007 0.86 PTGS1 (0.54) TRPV1SORT1
SCHEMBL31339996 0.79 CLK1 (0.47) MAPT
SCHEMBL31339978 0.78 BTK (0.48) TRPV1SORT1
SCHEMBL31340004 0.77 PIN1 (0.46) MAPTKMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL31339990 0.76 SORT1 (0.50) TRPV1SORT1
SCHEMBL31340012 0.75 KDM4E (0.46) TRPV1MAPTKMT2AALDH1A1MEN1
SCHEMBL31339962 0.75 LCK (0.59) TRPV1
SCHEMBL31339954 0.74 VNN1 (0.45) TRPV1MAPTSORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124202-A1 CD97 AND GSDME INTERACTION INHIBITOR HAVING ANTI-TUMOR ACTIVITY AND APPLICATION THEREOF JILIN UNIVERSITY (CN) 2026-05-07 — — US disclosed
EP-4725485-A1 CD97 AND GSDME INTERACTION INHIBITOR HAVING ANTI-TUMOR ACTIVITY AND APPLICATION THEREOF Jilin University (CN) 2026-04-15 — — EP disclosed
CN-119285557-A CD97 and GSDME interaction inhibitor with anti-tumor activity and application thereof 吉林大学 2025-01-10 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124202-A1 CD97 AND GSDME INTERACTION INHIBITOR HAVING ANTI-TUMOR ACTIVITY AND APPLICATION THEREOF GZMB, CD74, GSDMD TRPV1 1150/4885STAT3 451/4885MAPT 4802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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