Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1697181 | 0.87 | LMNA (0.37) | LMNAMAPT | |
| SCHEMBL3434962 | 0.77 | ELANE (0.33) | LMNAMAPT | |
| SCHEMBL1372005 | 0.74 | LMNA (0.36) | LMNACYP3A4MAPT | |
| SCHEMBL2709504 | 0.74 | CYP1A2 (0.41) | CYP3A4MAPTBCHEALOX5PDE5A | |
| SCHEMBL27600953 | 0.74 | CYP1A2 (0.51) | MCHR1LMNAMEN1NR1I2CHRM2 | |
| SCHEMBL17294439 | 0.72 | THRA (0.35) | MCHR1 | |
| SCHEMBL404718 | 0.72 | PPARA (0.41) | MCHR1LMNACYP3A4MAPTALOX5 | |
| SCHEMBL4248262 | 0.69 | SOAT1 (0.40) | — | |
| SCHEMBL28113968 | 0.68 | CYP1A2 (0.57) | MCHR1PDE5APDE4APDE4BPDE4C | |
| SCHEMBL28293909 | 0.68 | TSHR (0.41) | LMNAMEN1NR1I2CHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2015727-B1 | WATER RESISTANT SUNSCREEN FORMULATIONS WITH SULFOPOLYESTERS AND PHOSPHATE ESTER SURFACTANTS | EASTMAN CHEM CO (US) | 2010-01-06 | — | — | EP | disclosed |
| US-20070264216-A1 | Water resistant sunscreen formulas with sulfopolyesters and phosphate ester surfactants | EASTMAN CHEMICAL COMPANY | 2007-11-15 | — | — | US | disclosed |