Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434962 | 0.89 | ELANE (0.33) | LMNASMPD1NFKB1NFKB2RELA | |
| SCHEMBL3134741 | 0.87 | SGMS2 (0.34) | LMNAMAPT | |
| SCHEMBL1372005 | 0.83 | LMNA (0.36) | LMNANFKB1NFKB2RELANPC1 | |
| SCHEMBL17294439 | 0.83 | THRA (0.35) | SMPD1THRATHRBGSTA1GSTP1 | |
| SCHEMBL2709504 | 0.80 | CYP1A2 (0.41) | SMN1; SMN2MAPTTSHR | |
| SCHEMBL404718 | 0.78 | PPARA (0.41) | LMNASMN1; SMN2MAPTTSHR | |
| SCHEMBL27600953 | 0.77 | CYP1A2 (0.51) | LMNAMAPTTHRATHRB | |
| SCHEMBL28293909 | 0.73 | TSHR (0.41) | LMNASMPD1MAPTTSHRTP53 | |
| SCHEMBL1419945 | 0.73 | BID (0.49) | MAPTTSHR | |
| SCHEMBL15176184 | 0.71 | TSHR (0.40) | LMNATSHRTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575750-A2 | SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE | International Flora Technologies, Ltd. (US) | 2013-04-10 | — | — | EP | claimed |
| WO-2011149929-A2 | SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE | INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) | 2011-12-01 | — | — | WO | claimed |
| EP-3079777-A1 | EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR | Momentive Performance Materials Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015089035-A1 | EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| EP-2575750-A2 | SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE | International Flora Technologies, Ltd. (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011149929-A2 | SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE | INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) | 2011-12-01 | — | — | WO | disclosed |