SCHEMBL3434962

SCHEMBL3434962

CCCCCCOc1c(CC)cccc1-c1ccc(-c2ncncn2)c(OC)c1-c1cccc(CC)c1OCCCCCC

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
THRA P10827 2/20 0.32
THRB P10828 2/20 0.32
PTPN11 Q06124 2/20 0.32
LMNA P02545 3/20 0.31
PPARA Q07869 1/20 0.31
TLR8 Q9NR97 1/20 0.31
NFKB1 P19838 3/20 0.31
NFKB2 Q00653 3/20 0.31
RELA Q04206 3/20 0.31
NPC1 O15118 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
SMPD1 P17405 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697181 0.89 LMNA (0.37) THRATHRBLMNANFKB1NFKB2
SCHEMBL17294439 0.78 THRA (0.35) THRATHRBPPARATLR8SMPD1
SCHEMBL3134741 0.77 SGMS2 (0.34) LMNAMAPT
SCHEMBL1372005 0.76 LMNA (0.36) THRATHRBPTPN11LMNANFKB1
SCHEMBL2709504 0.76 CYP1A2 (0.41) PPARATLR8SMN1; SMN2MAPT
SCHEMBL404718 0.74 PPARA (0.41) LMNAPPARATLR8SMN1; SMN2MAPT
SCHEMBL28462674 0.69 SMPD1 (0.41) CNR2THRATHRBSMPD1
SCHEMBL17198731 0.68 CLK4 (0.39) NPC1SMN1; SMN2MAPT
SCHEMBL27982523 0.68 SOAT1 (0.46) PTPN11PPARA
SCHEMBL27600953 0.68 CYP1A2 (0.51) CNR2THRATHRBPTPN11LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126253-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, A SUITABLY SELECTED LIPOPHILIC POLYMER AND A CARRAGEENAN L'OREAL (FR) 2024-06-20 WO claimed
WO-2024126253-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, A SUITABLY SELECTED LIPOPHILIC POLYMER AND A CARRAGEENAN L'OREAL (FR) 2024-06-20 WO disclosed
EP-4353325-A1 SKIN CARE COMPOSITION CONTAINING ULTRAVIOLET WAVELENGTH-CONVERTING SUBSTANCE AND ALKYLENE OXIDE DERIVATIVE Shiseido Company, Ltd. (JP) 2024-04-17 EP disclosed
US-20230310291-A1 PHOTOPROTECTIVE COMPOSITION COMPRISING A GLYCINE BETAINE DERIVATIVE SURFACTGREEN (FR) 2023-10-05 US disclosed
EP-4188320-A1 PHOTOPROTECTIVE COMPOSITION COMPRISING A GLYCINE BETAINE DERIVATIVE Surfactgreen (FR) 2023-06-07 EP disclosed
US-20220202667-A1 COSMETIC COMPRISING ULTRAVIOLET WAVELENGTH CONVERSION SUBSTANCE SHISEIDO COMPANY, LTD. (JP) 2022-06-30 US disclosed
US-20220175637-A1 COMPOSITION COTAINING ULTRAVIOLET WAVELENGTH-CONVERTING SUBSTANCE AND HYDROPHOBIZED SILICA AND/OR HYDROPHOBIZED STARCH SHISEIDO COMPANY, LTD. (JP) 2022-06-09 US disclosed
US-20220175624-A1 POWDER COSMETIC CONTAINING ULTRAVIOLET WAVELENGTH-CONVERTING SUBSTANCE, AND METHOD FOR PRODUCING SAME SHISEIDO COMPANY, LTD. (JP) 2022-06-09 US disclosed
US-20220160605-A1 OIL-IN-WATER TYPE EMULSIFICATION COMPOSITION CONTAINING UV WAVELENGTH CONVERSION SUBSTANCE SHISEIDO COMPANY, LTD. (JP) 2022-05-26 US disclosed
US-20220160604-A1 EMULSION COMPOSITION COMPRISING ULTRAVIOLET WAVELENGTH CONVERSION SUBSTANCE AND ORGANIC OILY PHASE THICKENER SHISEIDO COMPANY, LTD. (JP) 2022-05-26 US disclosed
WO-2014105877-A1 LOW VISCOSITY META-STABLE PHOTOPROTECTION COMPOSITION L'OREAL (FR) 2014-07-03 WO disclosed
US-8486425-B1 Two-phase sunscreen composition L'OREAL (FR) 2013-07-16 US disclosed
US-20130142740-A1 SUNSCREEN COMPOSITIONS CONTAINING A NOVEL PRESERVATIVE SYSTEM LOREAL S.A. (FR) 2013-06-06 US disclosed
WO-2013080140-A2 SUNSCREEN COMPOSITIONS CONTAINING A NOVEL PRESERVATIVE SYSTEM L'OREAL (FR) 2013-06-06 WO disclosed
WO-2013080127-A2 COSMETIC OIL MOUSSE COMPOSITION L'OREAL (FR) 2013-06-06 WO disclosed
US-20130136701-A1 COSMETIC OIL MOUSSE COMPOSITION L'OREAL S.A. (FR) 2013-05-30 US disclosed
WO-2012110302-A2 COMPOSITION CONTAINING SCREENING COMPOSITES AND PARTICLES OF INORGANIC SCREENING AGENTS, WHICH ARE HYDROPHOBIC-MODIFIED WITH AN OIL OR WAX OF NATURAL ORIGIN L'OREAL (FR) 2012-08-23 WO disclosed
US-20100254923-A1 COMPOSITION AND PROCESS FOR PROTECTING CELLULAR TARGETS FROM AGING AND PHOTODAMAGE L'ORÉAL (FR) 2010-10-07 US disclosed
US-7357920-B2 Photostable photoprotective compositions comprising dibenzoylmethane and amide oil compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) L'OREAL (FR) 2008-04-15 US disclosed
US-20060083698-A1 Photostable photoprotective compositions comprising dibenzoylmethane and amide oil compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) L'OREAL (FR) 2006-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100254923-A1 COMPOSITION AND PROCESS FOR PROTECTING CELLULAR TARGETS FROM AGING AND PHOTODAMAGE RAD52, MMS19, XPA ELANE 3125/4885CNR1 4823/4885CNR2 4773/4885
US-20060083698-A1 Photostable photoprotective compositions comprising dibenzoylmethane and amide oil compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) NOTUM, CUTA, WEE1 ELANE 1546/4885CNR1 2100/4885CNR2 1605/4885
US-20220160605-A1 OIL-IN-WATER TYPE EMULSIFICATION COMPOSITION CONTAINING UV WAVELENGTH CONVERSION SUBSTANCE CD14, CD44, UGGT1 ELANE 979/4885CNR1 471/4885CNR2 585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.