Acetonitrile

Acetonitrile

SCHEMBL3135836

CC#N.[Na+].[OH-]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetonitrile. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL27949872 0.88
Acetonitrile SCHEMBL28253723 0.88
Acetonitrile SCHEMBL28167266 0.88
Acetonitrile SCHEMBL10790879 0.88
Acetonitrile SCHEMBL2170891 0.88
Acetonitrile SCHEMBL27901694 0.88
Acetonitrile SCHEMBL27516310 0.88
Acetonitrile SCHEMBL18838615 0.88
Acetonitrile SCHEMBL15638047 0.88
Acetonitrile SCHEMBL10523138 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116448860-A Norfloxacin sensor, preparation method and detection method thereof 成都师范学院 2023-07-18 CN claimed
CN-113248772-A Microfluidic preparation method of porous polyhydroxyalkanoate polymer microspheres, porous polymer microspheres prepared by microfluidic preparation method and application of porous polyhydroxyalkanoate polymer microspheres 中国科学院广州生物医药与健康研究院 2021-08-13 CN claimed
CN-109206554-B Ion imprinted polymer material for photo-reduction of hexavalent chromium and preparation and application thereof 华中科技大学 2020-10-16 CN claimed
CN-109206554-A A kind of ion imprinted polymer material of photo-reduction Cr VI and its preparation and application 华中科技大学 2019-01-15 CN claimed
CN-118294561-A Method for measuring methanesulfonate in transdermal patch by derivatization HPLC-UV method 上海世领制药有限公司 2024-07-05 CN disclosed
CN-116448860-A Norfloxacin sensor, preparation method and detection method thereof 成都师范学院 2023-07-18 CN disclosed
CN-115754100-A Extraction and detection method of polycyclic aromatic hydrocarbon 重庆市食品药品检验检测研究院 2023-03-07 CN disclosed
CN-115754100-A Extraction and detection method of polycyclic aromatic hydrocarbon 重庆市食品药品检验检测研究院 2023-03-07 CN disclosed
CN-110156761-B Compound containing coumarin-biphenyl skeleton, preparation method and application thereof 郑州大学 2022-08-09 CN disclosed
CN-111154035-B Tree-shaped molecular imprinting material and preparation method and application thereof 深圳市易瑞生物技术股份有限公司 2022-03-22 CN disclosed
CN-113347963-A Pharmaceutical composition comprising tamsulosin hydrochloride having excellent acid resistance and method for preparing the same 韩美药品株式会社 2021-09-03 CN disclosed
CN-113248772-A Microfluidic preparation method of porous polyhydroxyalkanoate polymer microspheres, porous polymer microspheres prepared by microfluidic preparation method and application of porous polyhydroxyalkanoate polymer microspheres 中国科学院广州生物医药与健康研究院 2021-08-13 CN disclosed
CN-108456154-A A kind of preparation method of N- tertbutyloxycarbonyls alkyl guanidine 昆明理工大学 2018-08-28 CN disclosed
CN-107235913-A The method of commercial scale high efficiency manufacture high-quality flibanserin 苏州科伦药物研究有限公司 2017-10-10 CN disclosed
US-20100004403-A1 High-Molecular Weight Conjugate of Combretastatins NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-01-07 US disclosed
EP-2042195-A1 POLYMER CONJUGATE OF COMBRETASTATIN Nippon Kayaku Kabushiki Kaisha (JP) 2009-04-01 EP disclosed
CN-1100750-C 15-deacetylated-13-amino acid substituted hypocrellin and its preparation INST OF PHOTOCHEMISTRY CHINESE (CN) 2003-02-05 CN disclosed
CN-1089755-C Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents PHARMACIA & UPJOHN SPA (IT) 2002-08-28 CN disclosed
CN-1299810-A 15-deacetylated-13-amino acid substituted hypocrellin and its preparation INST OF PHOTOCHEMISTRY CHINESE (CN) 2001-06-20 CN disclosed
CN-1222144-A Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents PHARMACIA & UPJOHN SPA (IT) 1999-07-07 CN disclosed