SCHEMBL3136597

SCHEMBL3136597

FC(F)(F)c1ccc([S+](c2ccccc2)c2ccccc2)cc1.O=S(=O)([O-])c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.38
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.37
KIF11 P52732 2/20 0.37
HDAC6 Q9UBN7 1/20 0.36
EEF2K O00418 2/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KAT6A Q92794 1/20 0.35
GPR27 Q9NS67 1/20 0.34
KCNK3 O14649 1/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
ACLY P53396 1/20 0.34
BACE1 P56817 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3127178 1.00 HSD11B1 (0.38) HSD11B1ALDH1A1TSHRKIF11HDAC6
SCHEMBL384538 0.87 CA1 (0.38) HDAC6
SCHEMBL2898477 0.87 HDAC11 (0.38) HSD11B1ALDH1A1HDAC6KEAP1NFE2L2
SCHEMBL3136634 0.87 HDAC11 (0.38) HSD11B1ALDH1A1HDAC6KEAP1NFE2L2
SCHEMBL3139768 0.86 ALDH1A1 (0.43) HSD11B1ALDH1A1TSHRKIF11EEF2K
SCHEMBL3132680 0.86 ALDH1A1 (0.43) HSD11B1ALDH1A1TSHRKIF11EEF2K
SCHEMBL3136606 0.84 PKM (0.37) HSD11B1ALDH1A1TSHRKEAP1NFE2L2
SCHEMBL3126164 0.84 PKM (0.37) HSD11B1ALDH1A1TSHRKEAP1NFE2L2
SCHEMBL503701 0.84 ALDH1A1 (0.45) HSD11B1ALDH1A1TSHRKIF11EEF2K
SCHEMBL3130383 0.84 RORC (0.39) HSD11B1ALDH1A1TSHRKIF11EEF2K

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 HSD11B1 718/4885ALDH1A1 139/4885TSHR 1087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.