Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.52 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410201 | 0.87 | PLA2G2A (0.48) | PLA2G2AAKR1A1AKR1B1TBXAS1MTNR1A | |
| SCHEMBL30711166 | 0.87 | PLA2G2A (0.48) | PLA2G2AAKR1A1AKR1B1TBXAS1MTNR1A | |
| SCHEMBL19410203 | 0.87 | PLA2G2A (0.48) | PLA2G2AAKR1A1AKR1B1TBXAS1MTNR1A | |
| SCHEMBL18028919 | 0.85 | ADRB2 (0.59) | PLA2G2AMTNR1AMTNR1BALDH1A1AKR1C3 | |
| SCHEMBL19427003 | 0.84 | PLA2G2A (0.46) | PLA2G2AAKR1A1AKR1B1TBXAS1MTNR1A | |
| SCHEMBL31688464 | 0.81 | PTGDR2 (0.54) | AKR1A1AKR1B1TBXAS1ALDH1A1HPGD | |
| SCHEMBL22188707 | 0.78 | ALDH1A1 (0.65) | TBXAS1ALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL22188706 | 0.78 | ALDH1A1 (0.65) | TBXAS1ALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL29552404 | 0.78 | ALDH1A1 (0.65) | TBXAS1ALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL18029182 | 0.78 | ALDH1A1 (0.49) | PLA2G2AMTNR1AMTNR1BALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | PLA2G2A 4715/4885AKR1A1 4462/4885AKR1B1 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.